Cuban vaccines doing well

The president of BioCubaFarma and the general director of the Finlay Vaccine Institute (IFV) gave an overview of the current state of Cuban vaccine candidates in the Mesa Redonda TV program.

OnCuba StaffbyOnCuba Staff February 5, 2021in Coronavirus, Health in Cuba

The president of the Biotechnologic and Pharmaceutical Industries Group (BioCubaFarma), Eduardo Martínez Díaz, affirmed this Thursday in the Mesa Redonda TV program that Cuba has sufficient capacities to produce different amounts of vaccines and begin the campaign that will immunize the entire population.

The specialist said that the four Cuban vaccine candidates are doing well, even though it is not possible to speak of their complete effectiveness until the planned studies are completed.

He highlighted, on the other hand, that they use technological platforms that have demonstrated safety and effectiveness in previous vaccines. And also that a variant can be dedicated to different population groups, such as convalescents, and that different doses are evaluated based on age.

Another of the potentialities of Cuban vaccines is that they require a freezing temperature of only two to eight degrees, and given the appearance of new variants of the coronavirus, they can include successive booster doses, he stressed.

He also said that only 108 million doses of vaccines have been applied in the world, just over 1% of the population, and that it has been concentrated in thirteen countries, which is why there are not enough quantities available at the moment.

The prices range from $10 to $35 a dose and must be lowered for the poorest countries to have access, he insisted. Cuba has been betting on a vaccine since the epidemic in China emerged, when the strategy began to take shape. As COVID-19 became a pandemic, this process was accelerated.

Finally, he explained that the four vaccine candidates use the same Receptor Binding Domain (RBD) antigen and that they were shown to have an immune response and the ability to inhibit virus entry.

For his part, Doctor Vicente Vérez Bencomo, general director of the Finlay Vaccine Institute (IFV), announced that in April the first million vaccines of that Center should be produced, and that the studies in the Soberana 01 and Soberana 02 vaccine candidates are advancing in order to achieve a generation of antibodies that prevent the virus from entering the cell.

In the case of Soberana 01, he said, three formulas were designed. In the trial with 60 people, divided into three groups, the vaccine was shown to be very safe: between 80 and 90% of those who received it had an induction of antibodies against the virus. Those who received a third dose increased to 95% their ability to generate antibodies with very high levels of neutralization, he added.

Based on this, he said, it is possible to enter Phase II-III scheduled for March, which should involve between 40,000 and 50,000 people and will have a placebo group. On its part, in its Phase I Soberana 02 showed safety and efficacy in terms of generating antibodies: more than 70% of the patients presented a strong response to the first dose.

Phase II-A included a population of up to 80 years of age with a very similar response even up to the second dose. He said they received authorization for Phase II-B with 810 participants, in which there are placebos, around 700 received the first administration of the product.

He added that they are currently designing Phase III of Soberana 02, also for March and with placebo, and that it will be implemented in the province of Havana in around 42,000 people.

By US-Cuba Normalization Committee

Organizing Committee, International and Nationwide Conference for the Normalization of US-Cuba Relations.

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    The vast majority of individuals in Indiana knew what was occurring during this procedure, and also they approved the transfer to an autonomous government which forbad enslavement. The prelude to the Constitution of 1816 reached far past the federal Costs of Rights. Some arrangements of the Constitution– education and learning, for instance– were visionary. Statehood held the assurance of a much better future for Indiana and its residents. The 1816 Constitution revealed the delegates’ hope and also positive outlook for that future.

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    Individuals developed porcelains and pottery as well as expanded their growing of plants. An early Timberland period team named the Adena people had elegant burial rituals, featuring log tombs beneath earth piles. In the middle of the Woodland period, the Hopewell individuals started to create long-range trade of products. Nearing completion of the phase, the people established very productive farming and also adjustment of farming, growing such crops as corn and also squash. Existing to the south of Great Lake Plains, it is a part of the Corn Belt as well as is defined by large productive plains. The above rundown map stands for the State of Indiana, located in the East-North-Central area of the United States.

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    The various other tribes were likewise encouraged to leave the state voluntarily via the repayment of aids and also land gives additional west. The Shawnee migrated westward to resolve in Missouri, and also the Lenape moved right into Canada. The other minor tribes in the state, consisting of the Wea, moved westward, mostly to Kansas. Jonathan Jennings, whose motto was “No enslavement in Indiana”, was elected governor of the state, defeating Thomas Posey 5,211 to 3,934 ballots. Jennings offered two terms as governor and afterwards went on to stand for the state in congress for an additional 18 years.

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  251. In addition, heavy steam cleansing includes much of the same negatives as utilizing soap and water. Your carpeting might still take days to completely dry and also will likely be covered with a detergent-based deposit that can continue to attract dirt. Nonetheless, lots of home owners are unsure concerning exactly how to properly clean their carpetings. If you’ve tried DIY rug cleansing, you understand that you’re usually consulted with mediocre results.
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    Allow us take a look at the numerous benefits as well as disadvantages of both these options to aid you make a decision which is extra fit for you. Carpeting cleaning recovers a rug’s look, color, and also snooze. You could be stunned at just how brand-new a rug takes care of a professional cleansing. Encapsulation utilizes a specialized foam that catches as well as locks dust deep in rug fibers. This foam increases as well as pulls that dust to the surface area with it. In turn, a professional can draw out that dirt as well as foam together.

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  253. And if you have tooth level of sensitivity that is continuous or problems you, do not wait on your next examination. Your dental specialist will have the ability to identify the reason as well as give you the therapy you require so you can return to delighting in food as well as beverages of any temperature level. If discomfort or pain lasts only for a couple of seconds quickly after consuming alcohol a warm or cool drink, the problem is not likely to be serious.

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    two times a week with a combination of cooking soft drink and also water. The solution will certainly aid to raise discolorations from in between your teeth without using harsh products. Mix a teaspoon of cooking soft drink with sufficient water to make a paste. Rinse thoroughly and then clean your teeth as typical.

    When a tooth receives way too much force or pressures at an uncommon angle, the nerve within overreacts. This is very usual after the dental professional positions a new filling in a tooth. If the bite is off, also simply a little, the tooth can be rather sensitive to temperature levels until he or she readjusts it back to typical. Oral level of sensitivity can additionally be a signs and symptom of other problems, including dental caries, gum tissue disease or a split tooth.
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    While these are one of the most usual reasons you may wind up with delicate teeth, it might also be from your everyday behaviors. Using cigarette items and bad dental hygiene will cause delicate dentin, gum illness, and loss of tooth enamel, also. If you see uncommon teeth level of sensitivity to cool or warm that continues for a number of days, make a visit with your dental practitioner.

    If the decay has reached the internal part of your tooth, a root canal may be required to eliminate the infected tissue. Not all tooth cavities are the same, and your dentist can inform you what kind you have after analyzing your teeth with oral tools. She or he might additionally utilize x-rays to validate areas of decay. If you have concerns or concerns regarding cavity prevention, please call our workplace.
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    Although the onset of dental cavity are responsive to treatment, the advanced phases may result in missing teeth along with a host of various other issues. The basic tenet for treating dental caries is for that reason early recognition of the problem, when the tooth can still be salvaged. Do you see when you clean and also floss this fuzzy sensation disappears? When we do not brush as well as floss the microorganisms and foods we eat build up and also develop a sticky material called plaque.

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